……通过肃清药企和 FDA 的种种腐败。我读过的两本书在这一块都提供了相当不错的数据和建议：Marcia Angell 写的《制药业的真相》（The Truth About Drug Companies），以及 John Abramson 写的《嗑药的美国》（Overdosed America）。问题多到根本列不完，但它们极其重要。第二件需要改变的事，是我们不仅需要更多关于医疗现状的数据，还需要……
…by cleaning up all the corruption in pharma and the FDA. The two books I've read that both have some pretty good stats and recommendations on this are: The Truth About Drug Companies by Marcia Angell Overdosed America by John Abramson The problems are way too numerous to list, but they're extremely important. The second thing that needs to change is that we need more data about the state of health care, as well as…
…especially considering the US is the only first world country where direct-to-consumer marketing is allowed for medications. Relevant book on this topic, and highly recommended read: https://www.amazon.com/Overdosed-America-Promise-American-Me...
……“对于一款 FDA 批准的、截至 2011 年市面上最赚钱的药物来说，这可是一个相当大的断言。”关于这个亚马逊上能买到一堆书。我读过一本不错的叫《嗑药的美国》（Overdosed America）。不过如果你在亚马逊搜“statin”，会有更多专门讲这个的书。“快速查阅文献发现立普妥（Lipitor）疗效更好 [3]（双盲、安慰剂对照、……
…This is a pretty big claim for a FDA-approved drug that was the most profitable drug on the market as of 2011." There are a bunch of books about this that you can get on Amazon. A good one I read is Overdosed America. But if you search on Amazon for 'statin' there are a lot more books that are specifically about this. "A quick literature search found Lipitor to be more efficacious[3] (Double blinded, placebo controlled,…
> There are a bunch of books about this that you can get on Amazon. A good one I read is Overdosed America. But if you search on Amazon for 'statin' there are a lot more books that are specifically about this. Make an argument here and cite your sources here, I'm not going to read a book just so I can respond…
……这是为了你以及其他感兴趣的人好。你也可以去查维基百科和 Google 学术上随手搜到的零散论文，但我认为你那样学不到太多干货。而在《嗑药的美国》（Overdosed America）里，其实真正相关的也就一两章。“顶级医学期刊上的论文 [1] 怎么样？”除非是 NIH 的大型试验、高引用的 meta 研究，或者是 IOM 的报告，否则真没太大价值。……
…did for the benefit of you and anyone else who is interested. You could instead read Wikipedia and random papers you find on Google scholar, but I don't think you'll really learn much that way. And in Overdosed America it's really only one or two chapters that are relevant. "How's a paper in a top tier medical journal[1]?" Not really worth much unless it's a large NIH trial, a well-cited meta study, or an IOM report.…
……在理论上说得通并不意味着实际就是真的。有好多书都讲到了药物试验存在的问题……Ben Goldacre 的《坏药》（Bad Pharma）、Marcia Angell 的《制药业的真相》（The Truth About Drug Companies）、《嗑药的美国》（Overdosed America）等等。这些书探讨的问题大体各不相同，所以在我看来（imho）都值得一读。
…makes sense on paper doesn't mean that it's actually true. There are a number of books about the issues with drug trials... Bad Pharma by Ben Goldacre, The Truth About Drug Companies by Marcia Angell, Overdosed America, etc. All of these books cover largely different issues, so imho it's worth reading them all.
……通过肃清药企和 FDA 的种种腐败。我读过的两本书在这一块都提供了相当不错的数据和建议：Marcia Angell 写的《制药业的真相》（The Truth About Drug Companies），以及 John Abramson 写的《嗑药的美国》（Overdosed America）。问题多到根本列不完，但它们极其重要。第二件需要改变的事，是我们不仅需要更多关于医疗现状的数据，还需要……
…by cleaning up all the corruption in pharma and the FDA. The two books I've read that both have some pretty good stats and recommendations on this are: The Truth About Drug Companies by Marcia Angell Overdosed America by John Abramson The problems are way too numerous to list, but they're extremely important. The second thing that needs to change is that we need more data about the state of health care, as well as…
……尤其是考虑到美国是唯一一个允许处方药直接面向消费者做广告（DTC）的第一世界国家。关于这个话题的必读相关好书推荐：https://www.amazon.com/Overdosed-America-Promise-American-Me...
…especially considering the US is the only first world country where direct-to-consumer marketing is allowed for medications. Relevant book on this topic, and highly recommended read: https://www.amazon.com/Overdosed-America-Promise-American-Me...
……“对于一款 FDA 批准的、截至 2011 年市面上最赚钱的药物来说，这可是一个相当大的断言。”关于这个亚马逊上能买到一堆书。我读过一本不错的叫《嗑药的美国》（Overdosed America）。不过如果你在亚马逊搜“statin”，会有更多专门讲这个的书。“快速查阅文献发现立普妥（Lipitor）疗效更好 [3]（双盲、安慰剂对照、……
…This is a pretty big claim for a FDA-approved drug that was the most profitable drug on the market as of 2011." There are a bunch of books about this that you can get on Amazon. A good one I read is Overdosed America. But if you search on Amazon for 'statin' there are a lot more books that are specifically about this. "A quick literature search found Lipitor to be more efficacious[3] (Double blinded, placebo controlled,…
> 关于这个亚马逊上能买到一堆书。我读过一本不错的叫《嗑药的美国》（Overdosed America）。不过如果你在亚马逊搜“statin”，会有更多专门讲这个的书。 在这把你的论点摆出来、把参考资料列出来，我可不会为了能回你一句就专门去读一本书……
> There are a bunch of books about this that you can get on Amazon. A good one I read is Overdosed America. But if you search on Amazon for 'statin' there are a lot more books that are specifically about this. Make an argument here and cite your sources here, I'm not going to read a book just so I can respond…
……这是为了你以及其他感兴趣的人好。你也可以去查维基百科和 Google 学术上随手搜到的零散论文，但我认为你那样学不到太多干货。而在《嗑药的美国》（Overdosed America）里，其实真正相关的也就一两章。“顶级医学期刊上的论文 [1] 怎么样？”除非是 NIH 的大型试验、高引用的 meta 研究，或者是 IOM 的报告，否则真没太大价值。……
…did for the benefit of you and anyone else who is interested. You could instead read Wikipedia and random papers you find on Google scholar, but I don't think you'll really learn much that way. And in Overdosed America it's really only one or two chapters that are relevant. "How's a paper in a top tier medical journal[1]?" Not really worth much unless it's a large NIH trial, a well-cited meta study, or an IOM report.…
……在理论上说得通并不意味着实际就是真的。有好多书都讲到了药物试验存在的问题……Ben Goldacre 的《坏药》（Bad Pharma）、Marcia Angell 的《制药业的真相》（The Truth About Drug Companies）、《嗑药的美国》（Overdosed America）等等。这些书探讨的问题大体各不相同，所以在我看来（imho）都值得一读。
…makes sense on paper doesn't mean that it's actually true. There are a number of books about the issues with drug trials... Bad Pharma by Ben Goldacre, The Truth About Drug Companies by Marcia Angell, Overdosed America, etc. All of these books cover largely different issues, so imho it's worth reading them all.