基因的分子生物学
Molecular biology of the gene
James D. Watson、Nancy H. Hopkins、Jeffrey W. Roberts、Joan Argetsinger Steitz · 初版 1965 年
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1977年重印
Hacker News 上怎么说
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Molecular biology of the gene
James D. Watson、Nancy H. Hopkins、Jeffrey W. Roberts、Joan Argetsinger Steitz · 初版 1965 年
1977年重印
正在加载完整评论……
……癌症”。Alberts 等人的《Molecular Biology of the Cell》。读完这本书后，你会对科学家在复杂细胞系统里面对的种种复杂性有深得多的理解。Watson 等人的《Molecular Biology of the Gene》。这本书不用多说，就是经典参考书。这三本书之所以出类拔萃，是因为它们所有的事实论述都直接附上了原始论文的链接……
…cancer". Molecular Biology the Cell (Alberts, etc). After you read this book you'll have a much better understanding of the full complexity that scientists have to deal with in complex cellular systems. Molecular Biology of the Gene (watson, etc). Can't say much about this book except that's it's a classic reference. What makes these three books exception is that they support all their factual claims with direct links to the papers…
我挺喜欢 Watson 的《Molecular Biology of the Gene》（别跟《Molecular Biology of the Cell》搞混了）。统计学阵营里，Jaynes 的书太赞了，可惜有点难。但先修要求其实很低，内容自成体系。Hoel, Port & Stone 的……
I'm quite fond of Watson's Molecular Biology of the Gene (not to be confused with Molecular Biology of the Cell). In the stats camp, Jaynes is fantastic, alas a bit difficult. But the prerequisites are very modest. It's self-contained. Hoel, Port & Stone's…
太对了。像中心法则（central dogma）这类基础概念学起来倒不是特别难，但如果你想真正搞明白后续的东西，深入理解它们至关重要。教材方面，James Watson 等人写的《Molecular Biology of the Gene》是理解中心法则（DNA -> RNA -> Protein）的绝佳切入点。细胞生物学方面，Alberts 等人的《Molecular Biology of the Cell》也是同理。《An Introduction to Systems…
Absolutely right. These basic concepts like the central dogma aren't especially hard to learn, but it's important to really understand them deeply if you want anything to make sense. Among textbooks, Molecular Biology of the Gene by James Watson et al. is a good starting point to understand the central dogma: DNA -> RNA -> Protein. Likewise Molecular Biology of the Cell by Alberts et al. for cell biology. An Introduction to Systems…
“细胞里的分子机器难道就是随机结合到质粒上，然后质粒让干啥就干啥吗？”算是吧。建议读读《Molecular Biology of the Cell》、《Molecular Biology of the Gene》和《Biochemistry》。书里详细解释了（人们观测到的现象）。TL;DR：是的，细胞内的机制确实会结合质粒。不，这并不是随机的——这是一个高度偏向性的过程。
"Does the machinery in the cell just randomly bind to plasmids and do what they say?" Sort of. Please read Molecular Biology of the Cell, Molecular Biology of the Gene, and Biochemistry. It's explained in detail (what people have observed). TL;DR: yeah, machinery in the cell binds to plasmids. No, it's not random- it's a highly biased process.
先看《Campbell Biology》，接着看《Molecular Biology of the Cell》和《Molecular Biology of the Gene》
Campbell Biology followed by Molecular Biology of the Cell and Molecular Biology of the Gene
……可穿戴设备上的数据分析。能赚钱吗？也许吧。令人兴奋且具有创新性吗？并没有。推荐一些阅读资料：《Synthetic biology: A Primer》、《An introduction to systems biology》（买 2020 版）、O'Reilly 的《Biobuilder》、《Molecular biology of the Gene》、《Campbell's Biology》。YouTube 频道：The Thought Emporium、Josiah Zayner、Khan Academy Biology、Biology Professor、Shomus Biology（前两个完全是讲生物工程的）
…analytics on wearables. Profitable? Maybe. Exciting and innovative? No. Some reading material: Synthetic biology: A Primer An introduction to systems biology (get the 2020 edition) O'Reilly: Biobuilder Molecular biology of the Gene Campbell's Biology YouTube Channels: The Thought Emporium Josiah Zayner Khan Academy Biology Biology Professor Shomus Biology (The first two deal exclusively with bioengineering)