终结阿尔茨海默病

The end of Alzheimer's

Dale E. Bredesen · 初版 2017 年

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在这本带来范式转变的著作中,医学博士 Dale Bredesen 为所有希望预防甚至逆转 Alzheimer's Disease(阿尔茨海默病)与认知能力衰退的人带来了真正的希望。The End of Alzheimer's 指出,AD 并非像目前治疗中所认为的那样属于单一病症,而是分为三种类型,并阐述了可能引发大脑“缩减”的 36 种代谢因素(微量营养素、激素水平、睡眠等)。该治疗方案向我们展示了如何通过改善生活方式(如补充 B12、戒断麸质或改善口腔卫生)来使这些因素恢复平衡。

Hacker News 上怎么说

  • Dale Bredesen 博士写的《阿尔茨海默病的终结》(The End of Alzheimer's)里提到了霉菌是一种病原途径,但我没印象说真菌也是。那本好书的核心观点是阿尔茨海默病其实有好几种不同类型,每种都有不同的……

    “The End of Alzheimer’s” by Dr Dale Bredesen mentions mold as one vector, but I don’t recall fungi as one. Key insights from that excellent book are that there are several different types of Alzheimer’s, each with a different…

  • ……羟氯喹只有和锌配合使用才有效,因为羟氯喹能促进细胞对锌的吸收。因此,锌才是关键成分。此外,我依稀记得《阿尔茨海默病的终结》(强烈推荐)这本书里大篇幅讨论过锌对神经健康的作用。

    …hydroxychloroquine being effectively only in conjunction with zinc as the hydroxychloroquine encourages cellular uptake of zinc. Ergo, zinc is the key ingredient. Further, I seem to recall the book "The end of alzheimer's" (high recommend) talked alot about zinc wrt neurological health.

  • > 愿意去看看比科学对照试验高一个维度的信息资源(可惜很多人并不愿意)。Dale Bredesen 博士写的《阿尔茨海默病的终结》通篇都是基于“科学对照试验”的,并且对生酮饮食得出了同样的结论。完全不需要你“脑洞大开” :)

    > willing to look at informational resources once step above scientific controlled studies (unfortunately many folks are not). The End of Alzheimer's by Dr Dale Bredesen is all about "scientific controlled studies" and comes to the same conclusion about keto diets. No need to be open-minded :)

  • Bredesen 写的《阿尔茨海默病的终结》一书假定阿尔茨海默病大约有 36 种危险因素。往往需要其中许多因素共同作用才会引发该病。这就是为什么单单隔离某一个因素的研究往往以失败告……

    The book "The End of Alzheimer's" by Bredesen postulates that there are around 36 risk factors for Alzheimer's. It takes many of them in combination to cause the disease. This is why studies isolating just one factor have failed to…

  • Bredesen 写过一本书叫《阿尔茨海默病的终结》,好像是这名儿。

    Bredesen has a book called The End of Alzheimer's, or something.

  • 我最近开始生吃大褐菇(portabella mushrooms),因为《阿尔茨海默病的终结》里提到它是具有神经保护作用的最强菌类。我完全不知道它们居然可能致癌。所以太感谢你了。书里根本没提是不是必须做熟了吃。我图方便就一直生吃来着。……

    I recently started eating raw portabella mushrooms because they are mentioned in "The End of Alzheimer's" as the most potent mushroom species for neuroprotective effects. I had NO idea they can be cancerous. So thank you. The book does not mention if they should be cooked or not. I eat them raw for convenience.…

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