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湿件

Wetware

Dennis Bray · 初版 2009 年

4人推荐
4位读者提及
6次提及

“像变形虫这样的单细胞生物,是如何过上如此复杂的生命的?它没有神经系统,又是如何捕食活的猎物、对光线、声音和气味做出反应,并展现出复杂的运动序列的?本书给出了一个惊人且新颖的答案。作者借助系统生物学这一新兴学科的发现,揭示了活细胞的内部化学机制本身就是一种计算形式。细胞由分子电路构成,这些电路能像电子设备一样执行逻辑运算,却具备独特的性质。Bray 认为,这种计算……”

Hacker News 上怎么说

  • ……连接,而不是大脑特定的生化过程。这是一种非常还原论的观点,极大地低估了甚至单个细胞的生物复杂性。有一本好书叫 Dennis Bray 写的《Wetware: A Computer in Every Living Cell》,详细探讨了即便在最简单的细胞中,也有多少功能和物理过程在运转,而这些往往被此类类比所忽视……

    …connections rather than the particular biochemical processes of the brain. It's a very reductionist view that drastically underestimates the biological complexity of even individual cells. There's a good book, Wetware: A Computer in Every Living Cell, by Dennis Bray going into detail on how much functionality and physical processes are at work even in the most simplest cells that is routinely ignored by these analogies…

  • 这里的另一个帖子里有人推荐了 Dennis Bray 的《Wetware: A Computer in Every Living Cell》,我读了觉得非常棒。当我们试图梳理这些复杂性时,把复杂的蛋白质相互作用看作逻辑电路的想法其实挺有道理的……

    Someone else in another thread on here recommended the book “Wetware: A Computer in Every Living Cell” by Dennis Bray and I really enjoyed it. The idea of looking at complex protein interactions as logical circuits kind of makes sense as we try to map out the complexities…

  • 读到这样的文章时,我就梦到了 Wetware:http://manybooks.net/titles/ruckerrother10rucker_ware_tetral... http://www.amazon.com/Wetware-Computer-Every-Living-Cell/dp/... 要是没有梦想,干嘛做这么多的工作?

    When I read articles like this, I dream of Wetware: http://manybooks.net/titles/ruckerrother10rucker_ware_tetral... http://www.amazon.com/Wetware-Computer-Every-Living-Cell/dp/... Why do so much work if you don't have a dream?

  • ……我们基于碳的系统在理论上是无法在硅基上复制的。有机系统传递的信息要丰富得多,而且主要是模拟信号,根本没有对应的硅基基础。Dennis Bray 的《Wetware, a computer in every living cell》详细阐述了即便在单个细胞中,信息处理也是多么多维和复杂,甚至单细胞生物也能执行复杂的……

    …our carbon based systems that can't be theoretically replicated on silicon. Organical systems convey much more, and predominantly analog signals, that don't have any sort of equivalent silicon basis. Wetware, a computer in every living cell by Dennis Bray goes into detail in how multidemnsional and complex the information processing in even individual cells is, down to single celled organisms executing complex…

  • 任何人如果想从计算角度寻找一篇在科学上更严谨的细胞生物学论述,不妨去读读 Dennis Bray 的《Wetware: A computer in every living cell》。这本书非常平易近人,而且尽管书名有点让人误解,但它绝没有主楼发的 Brian Ford 论文中那种荒唐的拟人化。

    Anyone interested in a more scientifically sound treatise of cellular biology and from a computational perspective should instead read "Wetware: A computer in every living cell" by Dennis Bray. It's very approachable and, despite its unfortunate title, has nothing to do with the absurd anthropomorphising suggested in the posted Brian Ford paper.

  • ……与传统理解的机制(比如突触传递、轴突运输和缝隙连接)无关的神秘过程。Dennis Bray 的《Wetware》是我读过最让人肃然起敬的书之一。生物有机体和细胞在信息计算以及存储/传递方面的丰富程度令人难以置信,简直无与伦比。我觉得这尤其……

    …mysterious process unrelated to conventionally understood mechanisms, such as synaptic transmission, axonal transport, and gap junction connections. One of the most humbling books I have ever read is Wetware by Dennis Bray. There is an unbelievable richness when it comes to computation and storage/transport of information in biological organisms and cells that are simply unparalleled. I feel this is especially…

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